| Disease | Family-genus of virus | Other animals affected | Comments |
| Foot-and-mouth disease (FMD) |
Picornaviridae Aphthovirus |
Most ruminants, wild and domestic. Several lab and wild animals. | US free of FMD. Eradicated nine times from US. |
| Vesicular stomatitis (VS) |
Rhabdoviridae Vesiculovirus |
Cattle, horses, certain wildlife, humans. | Enemic in Carolinas, Georgia. Periodic epidemics in manyther states. |
| Vesicular exanthema (VE) San Miguel sea lion virus (SMSLV) |
Caliciviridae Calicivirus |
Swine, sea lions, opal eye fish, several kinds of seals and other marine animals. | No VE since 1956. SMSLV in marine animals off coast of California may be a threat to swine. |
| Swine vesicular disease |
Picornaviridae Enterovirus |
Swine; occasionally humans | Never in US. Last outbreak in Italy, 1995. |